and today i was reading about innate immunity in HIV and I was feeling quite sorry for my prof. cos here was a nature paper where this other lab took a stab and it was the right stab - they looked in DCs, while my prof had looked at macrophages (since HIV can infect mp) and it was a wrong stab, sigh..
and then i remembered a talk that Paul Bieniasz gave us when I was at Rockefeller, and i remembered how he always seemed to be investigating random disjointed things about viruses, so that maybe he can make one nice finding and let the other people do the rest of the job while he moved on to something else. and i wonder if it is perhaps better to do that - where maybe the only similarity in the projects in your lab is the technique you use and have optimised, but the nature and subject of the project is quite different. because the lab i was in at Rockefeller does that too..